Examining the Evidence

Brian, a 49-year-old landscaper, lives with chronic post-traumatic stress disorder (PTSD).

He was recently diagnosed after presenting in distress, revealing a history of a very traumatic past.


Dr Michael Tam5th March 2019

Clinical scenario

Thanh, a 35-year-old pharmacist with chronic hepatitis B, consulted me recently.

He mentioned that he had been treating himself with a milk thistle (Silybum marianum) product and

Ahmed, a 25-year-old builder recently presented with acute low back pain.

I recalled an online discussion with some colleagues that lamented the evidence that paracetamol is not effective.1 


Dr Michael Tam details the case of a 25-year-old  patient with well-controlled bipolar affective disorder Clinical scenarioA 25-year-old man with bipolar affective disorder saw me recently. His

Nicky, a 48-year-old business executive, asked me for advice about deep vein thrombosis (DVT) prophylaxis prior to travel to the US.

She was a carrier for factor V Leiden. She had used enoxaparin

Contents:Clinical scenarioClinical questionCritical appraisalConclusionAre the results valid?Stat factsReferences CLINICAL SCENARIOZHONGYU, a 50-year-old allied health practitioner, presented with a

Alan, a 30-year-old office worker, looked miserable in my rooms with a runny nose, cough and sore throat.

He had a run-of-the-mill viral upper respiratory tract infection. He said his partner had

Karen, a 45-year-old registered nurse, presented with acute low back pain, a day after awkwardly transferring a patient.

She was otherwise well with no red flags. In an online discussion forum (GPs

I recently saw Leon, a three-year-old boy with acute otitis media.

As I was writing the prescription for amoxycillin, I remembered that there was a recent Australian study published on using yoghurt

I recently saw Rhys, a 29-year-old graphic designer suffering from an adjustment disorder with depressed mood, following the separation from his partner

 He mentioned an interest in St John’s wort

Matt, a 35-year-old lawyer, mentioned in passing that when he had a migraine, he took a couple of tablets of paracetamol with a double-shot espresso.

Caffeine is also available in combination over